Information for Third-party Applications on Mac
JavaScript injection via AppleScript will soon be disabled by default in Chrome stable. We’re making this change in order to protect users from injection of unwanted content.
Users who need this functionality can re-enable it by going to the menu bar, View > Developer > Allow JavaScript from Apple Events
Alternatively, applications that legitimately need to inject JavaScript into Chrome can do so by publishing an extension and using Native Messaging to communicate with their application process. For more information, see https://developer.chrome.com/extensions/nativeMessaging
For automation, developers can also use Telemetry: https://github.com/catapult-project/catapult/blob/master/telemetry/README.md